New Topical Drug Delivery System Pharmaceutical Organogel: A Review

نویسندگان

چکیده

A simple working definition of this term'Gel' is a soft, durable or solid material,containing both solids and liquid parts, where the part(gelator) exists as amesh / network aggregates, viz immobilize part liquid,a strong prevents from leaking flow, especially by local pressure. The gel called hydrogel Organogel depending on type component: water in living solvent organogels .Organogels have been discovered multipurpose tool pharmaceuticals for topical well transdermal delivery various drugs. They are semisolid classifications consists apolar phase phase. Gels form through mechanism entrapment polar segment into three-dimensional networked assembly Apolar inculded such isopropyl palmitate, myristate etc.an organogelator sorbiatanmonostearte, lecithin etc. consist Organogel, non-crystalline, nonglassythermoreversible (thermoplastic)solid materials viscoelastic system,can be considered semi-solid an immobilized preparation external apholar Apholar section closes between spaces structure built due to physical condition negotiation collectors compound properties gelators. Generally, these programs supported structurant integration molecules .These systems good transporter hydrophilic lipophilic therapeutic agents. present review describes number important organogel, different types organogel based organogelator, method applications pharmaceuticals.

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ژورنال

عنوان ژورنال: Asian journal of pharmaceutical research and development

سال: 2022

ISSN: ['2320-4850']

DOI: https://doi.org/10.22270/ajprd.v10i1.1088